Bing Cai
Ph.D.,Associate Research
Email: bcai@@gdiist.cn
Personal information:
Dr. Cai graduated from Shandong University with a B.S. degree in 2011 and received his Ph.D. degree in Neurobiology from the Institute of Neuroscience, Chinese Academy of Sciences (ION) in 2018. After completing his Ph.D., Dr. Cai conducted his postdoctoral research in Shanghai Institute of Materia Medica, Chinese Academy of Sciences (2018 - 2020). Dr. Cai joined the lab of somatosensory Neural Networks (LSNN) of the Guangdong Institute of Intelligent Science and Technology (GDIIST) as an Assistant Investigator in 2021.
Research interests:
His research mainly focused on understanding how neural network transmit somatosensory information through spinal projection neurons and dissecting the functional changes of spinal ascending projections under chronic pain by using a combination of viral tracing, electrophysiological, single-cell sequencing, optogenetic and behavioral techniques.
Publications：
1. Cai B*., Wu D*., Xie H*., Chen Y., Wang H-D., Jin S., Song Y-R., Li A-A., Huang S-Q., Wang S-S., Lu Y-J., Bao L., Xu F-Q., Gong H., Li C-L., and Zhang X. (2023) A direct spino-cortical circuit bypassing the thalamus modulates nociception. Cell Res., doi.org/10.1038/s41422-023-00832-0.
2. Zhang S., Cai B., Li Z., Wang K-K., Bao L., Li C-L., and Zhang X. (2022) Fibroblastic SMOC2 suppresses mechanical nociception by inhibiting coupled activation of primary sensory neurons. The Journal of Neuroscience., 42(4069-4086).
3. Wang B., Jiang B-W., Li G-W., Dong F., Luo Z., Cai B., Wei M-Y., Huang J-S., Wang K-K., Feng X., Tong F., Wang S-S., Wang Q., Han Q-J., Li C-L., Zhang X., Yang L., and Bao L. (2022) Somatosensory neurons express specific sets of lincRNAs, and lincRNA CLAP promotes itch sensation in mice. EMBO reports., 24(e54313).
4. Luo H., Cai B., Pan J., Shi H-X., Wang K-K., Zhong Y-Q., Lu Y-J., Bao L., Zhang X., and Li K-C. (2021) FXYD6 promotes thermal nociception by regulating TRPV1. Molecular Pain., 17(1): 1-15.
5. Li K-C., Cai B., Li C-L., and Zhang X. (2017) Presynaptic inhibition of nociceptive neurotransmission by somatosensory neuron-secreted suppressors. SCIENCE CHINA Life Sciences., 60: 1013-1018.
6. Wang F*., Cai B*., Li K-C*., Hu X-Y., Lu Y-J., Wang Q., Bao L., and Zhang X. (2015) FXYD2, a γ subunit of Na+,K+-ATPase, maintains persistent mechanical allodynia induced by inflammation. Cel Res., 25: 318-334
