SANDEEP KUMAR AGNIHOTRI
博士，研究助理
Email: sandy@@gdiist.cn
个人简介：
在尼赫鲁大学完成了博士学位，在哈尔滨工业大学神经生物学和帕金森病实验室的博士后，之后，Sandeep 博士加入上海中国科学院（CAS）神经科学研究所（ION）脑科学与智能技术卓越中心（CEBSIT），担任博士后研究员。Sandeep 博士加入燧人（上海）医疗科技有限公司是因为他对神经科学领域诊断神经退行性疾病的应用方面感兴趣和热情。Sandeep 博士获得了UGC颁发的优秀学生奖，并在生物技术硕士期间获得了全额 DBT（印度生物技术系）奖学金
研究方向：
[1] 认知神经科学与行为分析
[2] 认知障碍对神经退行性疾病的诊断
代表论著：
[1] Loss of PTEN-induced kinase 1 regulates oncogenic Ras-driven tumor growth by inhibiting mitochondrial fission. Dantong Zhu, Fengtong Han, Liuke Sun, Agnihotri SK, Ying Hu and Hansruedi Büeler. Frontiers in Oncology Cancer Genetics, 2022, May 5;12:893396. doi: 10.3389/fonc.2022.893396. PMID:35600352
[2] PINK1 deficiency is associated with increased deficits of adult hippocampal neurogenesis and lowers the threshold for stress-induced depression in mice. Agnihotri SK, Liuke Sun, Benjamin K. Yee, Ruifang Shen, Ravi S. Akundi, Lianteng Zhi, Marilyn J. Duncan, Wayne A. Cass and Hansruedi Büeler. BBR.2019 May 2; 363:161-172. doi: 10.1016/j.bbr.2019.02.006.PMID: 30735759
[3] Lack of PINK1 alters glia innate immune responses and enhances inflammation-induced, nitric oxide-mediated neuron death. Sun L, Shen R, Agnihotri SK, Chen Y, Huang Z, Büeler H. Sci Rep. 2018 Jan 10;8(1):383. doi: 10.1038/s41598-017-18786-w. PMID:29321620
[4] Loss of PINK1 leads to metabolic deficits in adult neural stem cells and impedes differentiation of newborn neurons in the mouse hippocampus. Agnihotri SK, Shen R, Li J, Gao X, Büeler H. FASEB J. 2017 Mar 21. pii: fj.201600960RR. doi: 10.1096/fj.201600960RR.PMID: 28325755
[5] Brain most susceptible to cadmium induced oxidative stress in mice. Agnihotri SK, Agrawal U, Ghosh I.J Trace Elem Med Biol. 2015 Apr;30:184-93. doi: 10.1016/j.jtemb.2014.12.008.PMID:25617233.
[6] Cadmium Toxicity Showing Organ Specific Signature of Responsiveness. Agnihotri SK, Ghosh I (2017) Perspectives in Environmental Toxicology. Springer International Publishing, Switzerland p, 203-214.doi: 10.1007/978-3-319-46248-6_4
[7] Mechanistic Effect of Heavy Metals in Neurological Disorder and Brain Cancer. Agnihotri SK, Kesari K.K. (2019) In: Kesari K. (eds) Networking of Mutagens in Environmental Toxicology. Environmental Science and Engineering. Springer, Cham doi: https://doi.org/10.1007/978-3-319-96511-6_2
