王宜敏

博士,研究员,研究组组长

Email: ywang@@gdiist.cn

个人简介:

王宜敏,研究员,神经网络数据计算与可视化研究组组长。2003年于复旦大学取得学士学位,2009年于新加坡南洋理工大学取得博士学位。研究方向包括脑科学图像大数据可视计算与分析、生物图像信息学、混合现实、计算机图形学、人工智能等。2022年起任广东省智能科学和技术研究院研究员和研究组长。主持国家自然科学基金委基金2项,上海市科委自然科学基金等项目多项。研究成果发表于 Nature,Nature Methods,Nature Communications 等杂志。

神经网络数据计算与可视化研究组:

本课题组围绕脑科学领域中产生的多尺度多模态数据开展一系列的计算、可视化和分析研究。基于发展新的可视化、人机交互和人工智能等方法,研究脑科学大数据管理、面向全脑图像的交互式神经元结构标注、神经元三维形态自动重建、多模态神经网络数据的表示与知识发现、神经网络结构预测与生成等问题。目标为鉴定神经元类型、解析神经环路特征、建立功能与结构的关联、构建和探索脑连接图谱提供有效的技术支撑和关键的科学发现。

课题组长期招收博士生。目前组内博士生由澳门大学、香港理工大学、北京师范大学等高校联合培养。此外,课题组也长期招收博士后、实习生等人员。

欢迎有意向者提前邮件联系(ywang@gdiist.cn)并提供简历。

代表论著:

1. Zhang, Lingli, Lei Huang, Zexin Yuan, Yuning Hang, Ying Zeng, …, Yimin Wang*, Hanchuan Peng*. “Collaborative Augmented Reconstruction for Scaled Production of 3D Neuron Morphology in Mouse and Human Brains.” Nature Methods, 2024. (*, co-corresponding authors)

2. Jie Chen*, Zexin Yuan*, ..., and Yimin Wang. Efficient and Accurate Semi-automatic Neuron Tracing with Extended Reality, IEEE TVCG (ISAMR 2024 special issue).  (* contributed equally)

3. Yang, Nianzu, Kaipeng Zeng, Haotian Lu, Yexin Wu, Zexin Yuan, Danni Chen, Shengdian Jiang, Jiaxiang Wu, Yimin Wang*, and Junchi Yan*. “MorphGrower: A Synchronized Layer-by-Layer Growing Approach for Plausible Neuronal Morphology Generation.” In Proceedings of the 41st International Conference on Machine Learning, 56749–92. PMLR, 2024. (*, co-corresponding authors)

4. Zhu, Xiaoqiang, Xiaomei Liu, Sihu Liu, Yalan Shen, Lihua You, and Yimin Wang*. “Robust Quasi-Uniform Surface Meshing of Neuronal Morphology Using Line Skeleton-Based Progressive Convolution Approximation.” Frontiers in Neuroinformatics 16 (2022). (*, corresponding author)

5. Jiang, Shengdian#, Yimin Wang#, Lijuan Liu#, Liya Ding, Zongcai Ruan, Hong-Wei Dong, Giorgio A. Ascoli, Michael Hawrylycz, Hongkui Zeng, and Hanchuan Peng. “Petabyte-Scale Multi-Morphometry of Single Neurons for Whole Brains.” Neuroinformatics 20, no. 2 (April 1, 2022): 525–36. (#, co-first authors)

6. Qu, Lei, Yuanyuan Li, Peng Xie, Lijuan Liu, Yimin Wang, Jun Wu, Yu Liu, et al. “Cross-Modal Coherent Registration of Whole Mouse Brains.” Nature Methods 19, no. 1 (January 2022): 111–18.

7. Peng, Hanchuan, Peng Xie, Lijuan Liu, Xiuli Kuang, Yimin Wang, Lei Qu, Hui Gong, et al. “Morphological Diversity of Single Neurons in Molecularly Defined Cell Types.” Nature 598, no. 7879 (October 2021): 174–81.

8. Muñoz-Castañeda, Rodrigo, Brian Zingg, Katherine S. Matho, Xiaoyin Chen, Quanxin Wang, Nicholas N. Foster, Anan Li, et al. “Cellular Anatomy of the Mouse Primary Motor Cortex.” Nature 598, no. 7879 (October 2021): 159–66.

9. BRAIN Initiative Cell Census Network (BICCN). “A Multimodal Cell Census and Atlas of the Mammalian Primary Motor Cortex.” Nature 598, no. 7879 (October 2021): 86–102.

10. Supple, Jack A., Daniel Pinto-Benito, Christopher Khoo, Trevor J. Wardill, Samuel T. Fabian, Molly Liu, Siddhant Pusdekar, et al. “Binocular Encoding in the Damselfly Pre-Motor Target Tracking System.” Current Biology 30, no. 4 (February 24, 2020): 645-656.e4. (selected as the cover article).

11. Yimin Wang*, Qi Li, Lijuan Liu, Zhi Zhou, Zongcai Ruan, Lingsheng Kong, Yaoyao Li, Yun Wang, Ning Zhong, Renjie Chai, Xiangfeng Luo, Yike Guo, Michael Hawrylycz, Qingming Luo, Zhongze Gu, Wei Xie, Hongkui Zeng, and Hanchuan Peng*. TeraVR Empowers Precise Reconstruction of Complete 3-D Neuronal Morphology in the Whole Brain.” Nature Communications 10, no. 1 (August 2, 2019): 3474. (*, co-corresponding authors)


王宜敏研究组